Arestin (Minocycline Powder)is a means by which a high concentration of antibiotic is delivered directly to the periodontal pocket non-surgically that can be inserted without a local anesthetic. The antibiotic level in the pocket reaches a substantially higher level around the tooth than can be attained from oral medication, however the antibiotic does not enter the bloodstream. As a result, there are no common antibiotic side effects or interactions with other medications you may be taking. This is a good option for early periodontal disease or in an area which has had previous surgery and has recurrent infection. People who suffer from significant medical problems and cannot tolerate surgical procedures may also benefit from this.